Question about 24 hr creatinine clearance

[LauraC]

This is my first time using this site. I was diagnosed with systemic lupus 20 years ago and have had two bad flares with 24 hour protein clearance over 6,000. I have been in remission since 1993 without any problems, but now my 24 hour creatinine clearance is creeping down. I am one who is either symptom free and in remission or very ill and on chemo. I feel very well and have no symptoms other than the 24 hour creatinine going as low as 61. Other numbers are normal. My rheumatologist is concerned but a urologist told me not to worry about it. I don't know why this number is decreasing in the absence of active disease. Any insight about this?

[wrwagner]

LauraC, Welcome to the DaVita forum! You have come to the right place. I am not familiar with Lupus, I am sure as folks get their day started they will be signing in and should be able to provide some insight to your concerns.

[chefnancy]

I am not familiar enough with lupus and its remissions to comment on this. If I were you I would ask a lot of questions of your nephrologist and/or urologist about these fluctuations. If they tell you not to worry about it, ask them why not.