The result puts Brisbane 12 points clear of second-placed Melbourne with three rounds to play, and seals a place in the Asian Champions League in 2015.
The trophy means the Roar also equal the Victory as the most Portugal Jersey successful club in the history of the A-League with two premierships and two championships.
The Roar enjoyed almost two-thirds of the possession and looked dangerous but the Victory were equal to the challenge, and also had their chances.
Lawrence pulled off two successive diving saves from quick-fire shots by Henrique and Dimitri Petratos in the 11th minute.
He denied Liam Miller an even better chance after some slick one-touch football just two minutes later.
Thomas Broich and Matt McKay were a constant headache for the Victory’s right-side defence but it was the visitors who could have taken a surprise lead after two gilt-edged chances in the 35th minute.
Kosta Barbarouses was expertly shut down by Diogo Ferreira firstly before Roar keeper Michael Theo expertly blocked a close-range shot by James Troisi.
Replacing the suspended Besart Berisha, Henrique was closely checked by Leigh Broxham who tested referee Peter Green’s patience and was given a yellow card (eighth for season) that forces him out of next weekend’s clash with Sydney FC.
Meanwhile, the highly-rated Perth Glory youngster Daniel De Silva has flown to Italy in the hope of landing a multimillion-dollar contract with a Serie A club.
Ronaldo 7 Jersey The Glory confirmed De Silva flew to Europe on Saturday with his family for discussions with key representatives from an unnamed club.
Should De Silva sign a deal, it is likely he will remain with the Glory until he turns 18. De Silva turned 17 this month, and is contracted to Glory until July 2015.